L-Carnosine is known as the 'longevity molecule '. Carnosine levels decrease with age  
starting at age 10! And decrease by 63% by the time you reach 70 years. (PMID: 15374064)

L-Carnosine is one of the most powerful antioxidants known. It's a heavy-metal scavenger. It s a super auto-regulator. And it stands alone when it comes to preventing
and reversing advanced glycation end products (AGEs) and cross-linking.

AGEs are created in your brain by sugars binding to amino acids, and are caused by a
variety of things, including certain foods and cooking techniques. Affecting word recall,
response time, and cognition. L-Carnosine is highly concentrated in your brain.

Spermidine is the strongest natural activator of autophagy known today. Autophagy is
your brain's internal recycling system. It breaks down and removes damaged proteins,
dysfunctional mitochondria, and cellular waste that accumulate with age. This cleanup
process is important for preserving healthy neurons. Without it, toxic proteins
accumulate, and brain cells die.

Spermidine has been shown in animal studies to help preserve synaptic density, increase
BDNF (brain-derived neurotrophic factor), and protect neurons in your hippocampus,
which are responsible for memory and recall.

A study published in the journal Scientific Reports in 2019 found that humans who
supplement with spermidine may slow memory loss as they get older. (PMCID: PMC6927957)

Full story:
https://www.quora.com/What-is-Best-supplement-for-longevity

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